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Abstract
Geraniol is a monoterpenoid and an alcohol. It is the primary part of rose oil, palmarosa oil, and citronella oil. It also occurs in small quantities in geranium, lemon, and many other essential oils. Geraniol has been used for many years in traditional medicine as anti-asthmatic, anti-allergic, anti-oxidant, antidiarrhoeic, antihepatotoxic, diuretic, tonic, and haemostatic, stomachic and anti-diabetic. In the present study, the animals were fed with HFD for 12 weeks to induce pathogenesis and the investigation was done whether oral administration of Gr on HFD fed rats could show protective effect on Vascular Dysfunction. The studies associated with HFD could cause hyperlipidemia, a risk factor for nephropathy. After 12 weeks, the lipid levels of HFD group were altered i.e., TG, TC, LDL levels increased and HDL levels decreased. Administration of Gr, for 6 weeks lowered the levels of TC, TG, LDL, while the levels of HDL was elevated. The results indicated that the Gr could attenuate the hyperlipidemia.