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Abstract
Colorectal tumors are formed due to alterations in cell adhesion in patients with colorectal cancer (CRC) at the locations of the colon and rectum in the large intestine. These tumors secrete several types of biochemical substances known as tumor markers which are usually protein in nature. Tumor markers are byproducts of cancer cells which are released into blood circulation. These tumor markers are helpful in the diagnosis and therapeutic management of colorectal cancer. The levels of tumor markers significantly increase along with the progression of the size of carcinoma in the biological system. Various therapeutic approaches like surgical, radiation, or adjuvant chemotherapy will result in decreasing levels of the tumor markers. Estimation of the relevant tumor markers are useful tool for the assessment of pathology as well as in the therapeutic assessment of the disease. This review highlighted the significance of tumor markers (CEA, CA19-9, and CA242) as powerful diagnostic and therapeutic tools for Colorectal Cancer.