Main Article Content
The objective to the paper emphasizes on the study of various models related to antimicrobial and antidiarrheal activity of Tinospora cordifolia. The plant also possesses various pharmacological activities including its use as antihyperglycemic, anti-inflammatory, antiarthritic, ant osteoporotic, enhance cognition (learning and memory), antidiarrheal and immunomodulatory effects. The current works aims to justify the folklore use of the whole plant of the Tinospora cordifolia for its antidiarrheal and antimicrobial potentiality. Tinospora cordifolia contains phytochemical constituent such as alkaloids, diterpenoid lactones, glycosides, steroids, sesquiterpenoid, phenolics, aliphatic compounds and polysaccharides. T. cordifolia is already an import- tent composition of many traditional Indian medicine formulations, both its purified stem proteins and the derived peptides by enzyme hydrolysis could be incorporated into food products or nutraceuticals or developed to be a safe and efficient drug for treating oxidative stress and related disorders. Pretreatment with Tinospora cordifolia extracts provide significant protection against castor oil and magnesium sulfate‑induced diarrhea, the extracts may presume to have antisecretory and preventive action towards CCK release.