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Abstract
The aim of this study was to investigate the anti-diabetic activity and mechanism of action of alcoholic flower extract prepared from Magnifera indica. The in vitro anti-diabetic study was done by evaluating the inhibitory effect of magnifera on the activities of alpha-amylase, Alpha amylase inhibition assay, Alpha glucosidase inhibition assay, yeast cell glucose uptake and inhibition of glucose diffusion assay methods. The significant results were observed in the alcoholic flower extracts. The α-glucosidse & α-amylase inhibition was in a dose dependent manner and glucose transport differs with the sample and glucose concentration. From the results of the study, it is inferred that, Magnifera indica flower possesses anti-diabetic activity. This work indicates that Flowers of Magnifera indica have an important long term anti-diabetic effect that can be well established to treat diabetes
Keywords
α-glucosidse, α-amylase and Magnifera indica.