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Abstract
The antiulcer activity of ethanolic extract of Asparagus racemosus leaves (EEAR) was investigated in pylorus ligation and ethanol induced ulcer models in experimental rats. In both models the common parameter determined was ulcer index. Ethanolic extract of Asparagus racemosus at a dose of 150 and 300mg/kg produced significant inhibition of the gastric lesions induced by pylorus ligation induced ulcer and ethanol induced gastric ulcer. The extract (150mg/kg and 300mg/kg) showed significant (p<0.05) reduction in gastric volume, free acidity and ulcer index as compared to control. This present study indicates that EEAR have potential anti-ulcer activity in both models. These results may further suggest that the extract was found to possess antiulcerogenic as well as ulcer healing properties, which might be due to its antisecretory activity.