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Abstract

Abelmoschus esculentus(okra), is a widely cultivated plant, particularly in tropical and subtropical regions. Pharmacognostical involves the study of macroscopic characteristics ofthe leaves of Abelmoschus esculentus are large,lobed,and havea characteristic dark green color.The leaf surface is rough with veins.The leaf’s internal structure consist of an like upper epidermis, lower epidermis,vascularbundle,spongyparenchyma,pallisade parenchyma,. Preliminary physicochemical studies confirmed the purity of the drug.The phytochemical investigation showedthe presence of Alkaloids, Flavonoids, Terpenoids, Anthraquinone glycoside, Phenolic compounds, Saponins.The results indicate that as the concentration of the ethanolic extract increased, the percentage of α-amylase inhibition also increased, demonstrating its potential as an anti-diabetic agent. At the highest concentration (400 μg/mL), the ethanolic extract achieved 63.14% inhibition, compared to 79.19% inhibition observed with acarbose.The results indicate that the concentration of the ethanolic extract achieved 75.64% inhibition, compared to 94.67% inhibition observed with acarbose. The IC₅₀ values indicate that the ethanolic extract has a higher concentration required for 50% inhibition compared to Captopril.

Keywords

Abelmoschus esculentus phytoconstituents pharmacological activity

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