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Abstract
Elettaria cardamomum seeds belonging to the family of Zingiberaceae. Many of its phyto constituents have been found to possess a wide spectrum of activities, such as antimicrobial, anti-inflammatory, antioxidant, and memory-enhancing. To better explore the bioactivity potential of Elettaria cardamomum we investigated the phytochemical screening In Vitro Antioxidant Activity using DPPH Radical Scavenging Assay, Total Antioxidant Capacity and Reducing Power Assay, anti-coagulant activity using Measurement of Bleeding Time, Prothrombin Time (PT), Activated Partial Thromboplastin Time (Aptt). The phytochemical analysis of Elettaria cardamomum extracts revealed a wide range of bioactive compounds, including saponins, flavonoids, terpenoids, tannins, alkaloids, steroids, anthraquinones, and reducing sugars. The anti-oxidant activity results showed a dose-dependent increase in DPPH radical scavenging activity, Both Elettaria Cardamomum extract and ascorbic acid demonstrate an increase in total antioxidant capacity with higher concentrations, in reducing power assay both Elettaria Cardamomum extract and ascorbic acid show a dose-dependent increase in reducing power. In anti-coagulant activity the results indicate the extract at 300 mg/kg showed a more pronounced increase in bleeding time, increased the prothrombin time, slightly increased aPTT, at higher dose showed more substantial effect, similar to aspirin. In conclusion the Elettaria cardamomum extract possess significant antioxidant and anticoagulant properties. Further research is needed to isolate specific active compounds.