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Abstract
The present investigation has been undertaken as study the anti-parkinson activity of ethanolic extract of syzygium cumini fruit.The plant Syzygiumcumini of family Myrtaceae an ayurvedic herb which is known for its significant medical properties. Experiments were conducted following standard procedures. The ethanolic extract of Syzygiumcumini were evaluated for their invivo antioxidant and anti-parkison properties and neurotransmitters level. The antiparkinson activity of EESC was evaluated using MPTP induced parkinson models. Levodopa was used as standard. Extracts treated groups showed higher invivo antioxidant and antiparkinson activities. They also showed higher activity in neurotransmitters level. EESC exhibited better anti-parkinson activity that of standard. The result may be attributed to the chemical constituents such as cyanidindiglycosides present in it which may be due to their individual or cumulative effect that enhanced anti-parkinson activity and provided scientific evidence of the ethnomedicinal futures of syzygiumcumini fruit. These findings could justify the inclusion of this plant in the management of parkinson’s disease.