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Abstract

Since plants possess diverse medicinal properties because of having some specific active ingredients, different organs of the same plant species may be effective against different diseases, or in some cases, if one organ has a healing effect, the other may be toxic, due to the presence of different active ingredients. The genus Samanea saman is the largest and more diverse of the family, comprising more than 560 species of vines, lianas, trees, and shrubs, commonly used for their fruits and derivatives, and as ornamental and medicinal plants. Samanea saman is a prominent medicinal plant with major phytoconstituents such as flavonoids, glycosides, alkaloids, phenolic and steroids constituents those are potent for potential therapeutic practice. The present aim of the research work is to assess the anthelmintic activity of ethyl acetate extract of Samanea saman root against Indian earth worms. Albendazole was used as standard reference and saline water as control. The anthelmintic activity of ethyl acetate extract was comparable with that of standard drug albendazole. At the concentration of 100 mg/ml extract of showed similar significant activity as compared to the standard drug albendazole (100 mg/ml), the time of paralysis and death being 15 min and 25 min respectively. Further work will emphasize the isolation and characterization of active principles responsible for anthelmintic activity of Samanea saman.      

Keywords

Samanea saman Indian earth worms phytoconstituents anthelmintic activity albendazole

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