Main Article Content
Abstract
Sidaacutais shrub indigenous to pantropical areas, widely distributed in regions and found in pastures, waste lands, cultivated lands, roadsides, lawns and planted forests. Sidaacuta is ethanomedically used as treatment of diuretic, asthma, fever, headache, cough, cold, ulcer, anthelmintic, snake bite, urinary disease, female disorders, sedative, eczema, kidney stone, elephantiasis, testicular swelling, poultice for dandruff, rheumatic affections, facial paralysis, pulmonary tuberculosis and gonorrheae.
Methods
Preparation of hydroalcoholic extract of Sidaacuta and Hydro-alcoholic extract of Sidaacuta was evaluated for its antidiabetic studies by alpha amylase method.
Results
The inhibitory concentration (IC50) of Hydro-alcoholic extract of Sidaacuta against alpha amylase inhibitory effect was found to be 17.10µg/ml in comparison with acarbose 9.27µg/ml. Hydro-alcoholic extract of Sidaacutashowed significant alpha amylase inhibitory effect when compared with acarbose. Hence preparation may be formulated with hydro-alcohol and aqueous extract.
Conclusion
The present research draws the conclusion that Sidaacutaplant showed mild antidiabetic effect, which may be due to the phytoconstituents.