Evaluation of antipyretic activity of leaf extracts of Triumfetta rhomboidea Jacq

Abstract

A study was carried out to evaluate the anti-pyretic potential of the ethanol extract of Triumfetta rhomboidea leaves using Yeast induced pyrexia in wister albino rats. Rectal temperatures were recorded before and after inducing pyrexia at interval of one hour for three hours. The leaf extract at oral doses of 100 and 200 mg/kg showed significant reduction in yeast-provoked elevated temperature in a dose-dependent manner and the anti-pyretic effect was comparable to that of standard antipyretic agent paracetamol (200 mg/kg). The effect also extended up to 3 hours after the drug administration.